Why Does the Cell Membrane Have a Glycocalyx?

💡 The Answer

• The glycocalyx is a fuzzy coat of glycoproteins and glycolipids on the extracellular surface of the membrane.
• It mediates cell-cell recognition, adhesion, and communication, such as identifying self vs. foreign cells.
• The glycocalyx also provides a protective barrier against mechanical and chemical stress.
• In blood vessels, it regulates permeability and prevents leukocyte adhesion under normal conditions.