How Does Huntington's Disease Progress Over Time?

💡 The Answer

• Huntington's disease presents as a triad of progressive psychiatric, cognitive, and motor symptoms.
• The earliest symptoms are often subtle mood or mental/psychiatric problems.
• These psychiatric symptoms typically appear before any motor symptoms.
• Definitive physical symptoms include lack of coordination and an unsteady gait.
• Over time, the basal ganglia region of the brain gradually becomes damaged.