biology

Can the earliest symptoms of Huntington's disease be non-motor?

šŸ’” The Answer

  • Huntington's disease presents with a triad of psychiatric, cognitive, and motor symptoms.
  • The earliest symptoms are often subtle mood or mental problems.
  • These psychiatric symptoms can precede motor symptoms for many people.
  • Definitive physical symptoms like coordination problems appear later.
  • This sequence explains why early diagnosis is challenging.

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